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Zigang Dong Selected Research

Agar

9/2016In vitro Anticancer Activities of Some Triterpene Glycosides from Holothurians of Cucumariidae, Stichopodidae, Psolidae, Holothuriidae and Synaptidae families.
10/2015Aschantin targeting on the kinase domain of mammalian target of rapamycin suppresses epidermal growth factor-induced neoplastic cell transformation.
2/2014Targeting of magnolin on ERKs inhibits Ras/ERKs/RSK2-signaling-mediated neoplastic cell transformation.
12/2012RSK2 as a key regulator in human skin cancer.
4/2010The anticancer effects of actinoporin RTX-A from the sea anemone Heteractis crispa (=Radianthus macrodactylus).
10/2008Resveratrol directly targets COX-2 to inhibit carcinogenesis.
9/2008Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation.
3/2008Anticancer activity of 3-demethylubiquinone Q2. In vivo experiments and probable mechanism of action.
3/2007Direct inhibition of insulin-like growth factor-I receptor kinase activity by (-)-epigallocatechin-3-gallate regulates cell transformation.
1/2006Evaluation of cancer-preventive activity and structure-activity relationships of 3-demethylubiquinone Q2, isolated from the ascidian Aplidium glabrum, and its synthetic analogs.

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Zigang Dong Research Topics

Disease

252Neoplasms (Cancer)
04/2024 - 02/2000
82Carcinogenesis
04/2024 - 12/2002
39Skin Neoplasms (Skin Cancer)
01/2021 - 12/2002
30Esophageal Squamous Cell Carcinoma
04/2024 - 01/2017
29Colonic Neoplasms (Colon Cancer)
04/2024 - 10/2008
24Lung Neoplasms (Lung Cancer)
12/2023 - 05/2010
23Colorectal Neoplasms (Colorectal Cancer)
04/2024 - 07/2007
21Inflammation (Inflammations)
01/2024 - 05/2008
20Melanoma (Melanoma, Malignant)
01/2023 - 08/2005
19Neoplasm Metastasis (Metastasis)
01/2024 - 06/2007
17Neoplastic Cell Transformation
03/2016 - 06/2004
15Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2023 - 06/2013
12Breast Neoplasms (Breast Cancer)
08/2023 - 09/2006
10Stomach Neoplasms (Stomach Cancer)
05/2023 - 01/2012
9Esophageal Neoplasms (Esophageal Cancer)
01/2022 - 05/2016
9Nasopharyngeal Carcinoma
12/2016 - 10/2011
6Infections
01/2022 - 12/2012
6Prostatic Neoplasms (Prostate Cancer)
01/2018 - 07/2012
5Obesity
10/2023 - 10/2008
5Body Weight (Weight, Body)
01/2021 - 01/2013
5Leukemia
09/2016 - 06/2007
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2022 - 01/2017
4Carcinoma (Carcinomatosis)
05/2016 - 01/2012
4Pancreatic Neoplasms (Pancreatic Cancer)
12/2015 - 11/2010
3Type 2 Diabetes Mellitus (MODY)
10/2023 - 01/2018
3COVID-19
10/2022 - 01/2020
3Hypoxia (Hypoxemia)
01/2022 - 05/2010
3Hyperplasia
01/2021 - 11/2015
3Parkinson Disease (Parkinson's Disease)
01/2020 - 07/2009
3Pain (Aches)
03/2016 - 02/2009

Drug/Important Bio-Agent (IBA)

66Proteins (Proteins, Gene)FDA Link
04/2024 - 07/2003
37Phosphotransferases (Kinase)IBA
12/2023 - 02/2000
22Protein Kinases (Protein Kinase)IBA
02/2024 - 01/2003
21CarcinogensIBA
01/2022 - 02/2000
18Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
03/2024 - 07/2007
16Epidermal Growth Factor (EGF)IBA
09/2016 - 04/2003
12ErbB Receptors (EGF Receptor)IBA
01/2022 - 01/2008
12Transcription Factor AP-1 (Transcription Factor AP 1)IBA
01/2018 - 01/2003
11Histones (Histone)IBA
10/2017 - 07/2005
10Small Interfering RNA (siRNA)IBA
05/2020 - 06/2004
10AgarIBA
09/2016 - 01/2006
9Biomarkers (Surrogate Marker)IBA
01/2021 - 08/2014
9Transcription Factors (Transcription Factor)IBA
11/2020 - 01/2003
9PhytochemicalsIBA
05/2017 - 04/2010
8FlavonoidsIBA
01/2021 - 12/2010
7ResveratrolIBA
02/2024 - 04/2002
7Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2021 - 10/2009
7Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2020 - 04/2010
7TeaIBA
09/2014 - 01/2003
7Cyclooxygenase 2 (Cyclooxygenase-2)IBA
02/2013 - 07/2008
6Mitogen-Activated Protein KinasesIBA
12/2023 - 06/2006
6Gefitinib (Iressa)FDA Link
08/2023 - 07/2013
6IsoflavonesIBA
08/2023 - 11/2007
6AntioxidantsIBA
01/2023 - 07/2008
6ArsenicIBA
09/2012 - 02/2000
5CateninsIBA
01/2022 - 12/2013
5Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2022 - 12/2002
5UbiquitinIBA
12/2021 - 06/2012
5Therapeutic UsesIBA
04/2021 - 05/2016
5EnzymesIBA
12/2019 - 06/2006
5Cyclin-Dependent Kinase Inhibitor p16IBA
06/2016 - 08/2005
5Serine (L-Serine)FDA Link
06/2012 - 07/2002
4Messenger RNA (mRNA)IBA
04/2024 - 09/2012
4Glucose (Dextrose)FDA LinkGeneric
01/2022 - 09/2006
4Aurora Kinase AIBA
01/2022 - 03/2019
4Annexin A5IBA
03/2021 - 06/2013
4Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2021 - 09/2013
4DNA (Deoxyribonucleic Acid)IBA
01/2021 - 03/2013
4Capsaicin (Zostrix)FDA Link
03/2020 - 09/2010
4NF-kappa B (NF-kB)IBA
09/2019 - 01/2003
4MicroRNAs (MicroRNA)IBA
04/2019 - 11/2012
4p38 Mitogen-Activated Protein KinasesIBA
01/2019 - 06/2011
4daidzeinIBA
05/2017 - 11/2007
4ProstaglandinsIBA
01/2017 - 10/2009
4Protein Isoforms (Isoforms)IBA
01/2017 - 03/2002
4Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
09/2015 - 07/2012
4epigallocatechin gallate (epigallocatechin-3-gallate)IBA
09/2011 - 03/2008
3Monoclonal AntibodiesIBA
06/2023 - 01/2020
3costunolideIBA
10/2022 - 01/2021
3CalciumIBA
02/2022 - 09/2005
3Thromboxane A2 (A2, Thromboxane)IBA
01/2022 - 01/2017
3Tyrosine Kinase InhibitorsIBA
01/2022 - 07/2013
3Propidium (Propidium Iodide)IBA
03/2021 - 08/2019
370-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
01/2021 - 04/2009
3Urethane (Ethyl Carbamate)IBA
01/2021 - 01/2018
3Caspase 3 (Caspase-3)IBA
10/2020 - 04/2009
3Aurora Kinase BIBA
01/2020 - 01/2013
3polypeptide 3 90kDa ribosomal protein S6 kinaseIBA
09/2019 - 01/2011
3Ribosomal Protein S6 Kinases (S6 Kinase)IBA
08/2019 - 05/2013
3leukotriene A4 hydrolaseIBA
06/2019 - 07/2009
3Phosphatidylinositols (Phosphatidylinositol)IBA
01/2019 - 06/2013
3N,N'-dinitrosopiperazineIBA
12/2018 - 10/2011
3Cyclin D1IBA
10/2018 - 03/2014
3Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
10/2017 - 01/2016
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2017 - 04/2010

Therapy/Procedure

62Therapeutics
04/2024 - 02/2000
22Chemoprevention
05/2023 - 01/2003
8Drug Therapy (Chemotherapy)
05/2021 - 06/2006
7Oral Administration
01/2020 - 11/2006
3Radiotherapy
01/2023 - 06/2015